PGP Scoring and Ranking Project

This project is about the scoring and ranking of phenotypes and participants of the Harvard Personal Genome Project (PGP). The objectives are,

• Keep track of the phenotypes available from the PGP.
• Incentivize participants to contribute phenotypes and other data to their public PGP profile.
• Inform scientists world-wide about potential phenotypes and participants of the PGP for research purposes.
• Can be use as a tool to prioritize participants for sequencing, generation of cell-lines and other research endeavors.

How is the scoring and ranking done?

• Phenotype Score

The phenotype score indicates the number of PGP participants that provided a valid value for the phenotype. The higher the score implies more participants reported the status of the phenotype in their PGP public profile. Some of these phenotypes will be used as input to calculate the participant's P-index. Click here to see Phenotype Scores.

• P-index

The P-index is a normalized score of every PGP participant and is used to rank the participants of the PGP. Briefly, participants gets awarded the number of points equal to the sum of phenotype scores that the participant has valid phenotypes for. The number of points is then divided by the theoretical maximum number of points (which is equal to the sum of all phenotype scores) multiplied by 100. This will result in a number from 0 to 100, where 0 indicate that the participant have reported no valid phenotypes while 100 indicate that the participant reported every scorable phenotype present in the PGP. Click here to see participant's P-indexes and rank.

Ranking Frequency

Uploading Phenotypes as a PGP participant

Citation

Funding